Ilya and Zhenya love each other but Zhenya keeps her feelings. She finds out that her son’s fiancée is pregnant from another man. This makes the spouses close together again. Ilya is jealous. A prima of a local theatre is taken to the hospital.
A new chief of department Ilya Sokolov arrives to a hospital in Tula from Moscow. At the same time a patient with heavy injuries is delivered to the hospital. A surgeon Yevgenia Koroleva makes a decision to amputate his arm.
The new chief starts to bring in his own rules and Zhenya finds it hard to get on well with him. All the hospital crew is engaged helping bride who got seriously injured during her own wedding.
An old man, who survived a hypertensic crisis, is taken to the hospital. But there’s another diagnosis made during the checkup. Zhenya and Vyacheslav argue about the methods of treatment of old people, while Ilya gets into a conflict with Stepan, Evgenia’s husband.
A boy jumped out of the window from the second floor because of his parents’ divorce. He is taken to the hospital. Zhenya fails to be at the railway station in time to meet her son. She pinballs between her work and her family which turns into a new conflict with her husband.
Because of the area prefect’s negligence a house’s collapse happens. Everyone is busy saving the wounded and the injured. Stepan’s and Zhenya’s relationship is ruined, and in the meantime Ilya tells Slava the main cause of his arrival in Tula.
A mysterious man from London is taken to the hospital after being poisoned with a clophelin. Stepan takes care of this case. Zhenya has to work with him and Galina. Suddenly the relationship with Ilya gets right.
Zinaida gets back to the hospital after been released with osteochondrosis. Now the scans show a tumor and the pain gets harder. Vyacheslav complains that the crew in the hospital isn’t even able to come up with a right diagnosis.
All the crew gossip around the article dedicated to Sokolov’s past. Koroleva is the only one who defends Ilya. Zhenya rumbles with Stepan and wants everything back. Meanwhile the surgeons try to save a young woman but her condition gets worse.
Zhenya and Ilya ignore each other. But they can’t keep their feelings when they are both left on a night shift. Lana, Ilya’s fiancée, arrives from Moscow, while Stepan asks Galya to take the son home. The young man carries his girlfriend with a pyelonephritis on his hands to the hospital.
Ilya doesn’t know how to behave with Zhenya. She thinks there can’t be anything between them. Lana tries to make peace with Ilya and Zhenya sees she won’t manage to compete with a young a beautiful girl. In the meantime Galina’s son gets into the hospital shot and wounded.
Ilya is angry that Zhenya ignores him. Suddenly Vyacheslav finds out about two of them and informs Lana. She covers Ilya with concern and tenderness, and she seduces him. Zhenya hides the truth from the son that she and Stepan broke up. A famous business lady gets into the hospital with a compound fracture.
Zhenya files for divorce. Stepan wants to get back but Zhenya can’t forgive his betrayal. Lana insists that Ilya should return to Moscow and makes a proposal herself, which Ilya can’t resist. But he doesn’t come at the time and Lana goes back alone. Meanwhile the hospital crew tries to save people who got into the car crash accident.
The collectors are robbed near the supermarket. A wounded thief comes to the hospital and takes Zhenya as a hostage. He demands to remove a bullet from his leg and not to inform the police. Zhenya persuades him to surrender.
Roman and his girlfriend arrive and inform that they wait for a baby. Zhenya and Stepan pretend to be a happy family. Lana calls Ilya and says she wants to be with him, and Zhenya hears their conversation. In the meantime a man bitten by the dog is taken to the hospital…
Ilya and Zhenya love each other but Zhenya keeps her feelings. She finds out that her son’s fiancée is pregnant from another man. This makes the spouses close together again. Ilya is jealous. A prima of a local theatre is taken to the hospital.
Stepan and Zhenya tell the truth to the son about his bride, but he already knows everything. The parents realize that he spoils his life, but he doesn’t listen to them and leaves to Moscow. Stepan and Zhenya decide to start all over again, meanwhile Lana visits Ilya.
Zhenya and Stepan try to save their family. Ilya takes it close to the heart but he can’t do anything and turns it all to a business relationship. Lana hopes Ilya would come back to Moscow. A man wounded in the heart tries to convince everyone it was just an accident.
Galina’s son gets into a bad company but Stepan helps him out. Lana gets bored and she asks Ilya to make peace with her father. Zhenya shows that everything is going well. Vasiliy refuses to hospitalize an old woman, while her husband and his friend seize the ambulance car.
Zhenya and Stepan both think another one has forgotten about the divorce on the day of it. Soon they find out that they both remember but are afraid to talk about it. Zhenya saves an electrician who was given an electric shock.
A jockey crushed by a horse is taken to the hospital. Ilya does his best but the patient dies. Ilya takes it very emotional and a new passion fires up between him and Zhenya. Galya realizes that Zhenya and Ilya are lovers.
Galina tells Stepan that Zhenya and Ilya have an affair. Stepan is desperate and makes a proposal to her. Zhenya sees that something is wrong with Hippocrates. Olga’s father is taken to the hospital with serious wounds received during the hunting.
Ilya is happy as they don’t need to hide anything with Zhenya anymore, but Zhenya asks not to hurry. Lana doesn’t want to give up. Professor Lanskoy asks Slava to look after Ilya and promises to help his career. Slava agrees to help.
Ilya invites Zhenya to his place. Slava spies on them and Zhenya feels an invisible presence of Lana. Galina’s son starts to call Stepan as a father. Zhenya learns that Hippocrates is seriously ill, but the chief doctor doesn’t want to discuss it. Zhenya saves a girl from the circus in the hospital.
Zhenya tells Ilya about her feelings. She asks Stepan to take all his things as soon as possible and asks Ilya to move to her place. Slava becomes the chief doctor’s deputy and in the meantime a boy with a rare genetic disease is saved in the hospital.
Ilya is happy, but Lana’s arrival surprises him. He takes additional hours not to spend any nights with her. But Lana doesn’t give up. Hippocrates confesses that Slava’s appointment is an order from above. Lana tries to be a part of the crew to be closer to Ilya and she is responsible that a small boy almost dies.
Zhenya finds out that Ilya works 24/7 and Lana lives in his apartment. She asks Ilya to make a decision but he can’t throw Lana out as he is much obliged to her family. Stepan comes to Zhenya to take the remaining things and stays at night. Zhenya learns that Hippocrates refused from any treatment.
Galina realizes that Stepan didn’t keep his word and got back to Zhenya, though he lies that he’s been working. Galya pretends she believes him. Zhenya and Ilya try to behave formally again and Zhenya tells him about Hippocrates as she needs to share this with somebody. Lana starts an open scandal.
Ilya chooses Zhenya, leaving Lana and her father’s relations, as he decides to achieve everything himself. Zhenya loves Ilya but she feels bad for Stepan. Slava sets Hippocrates up, and in the meantime a famous singer loses her voice and Zhenya has only a few hours before the concert to save the day.
Zhenya and Ilya are happy. Galya forgives Stepan but realizes that it’s all because of Zhenya’s choice. Everybody learns about the chief doctor’s illness. A young judo fighter is taken to the hospital and Zhenya finds out that he keeps his diagnosis in secret to participate in the underground fights.
Ilya talks to Moscow colleagues and learns that Hippocrates can be saved if the operation is made immediately. Zhenya tries to persuade her boss to go, but it is useless. She remembers that Hippocrates has a son, but he doesn’t want to hear anything about father. Two women are taken to the hospital and Zhenya learns that they are a wife and a lover of the same man.
Stepan and Zhenya get the divorce and he plans a wedding with Galya. Zhenya finds the right words to make Mikhail meet his father. The son and the grandson persuade Hippocrates to go to Moscow for the operation.
Ilya and Zhenya make plans for the future. Professor Lanskoy tries to help his daughter and finds a good place in a Moscow clinic for Ilya. Suddenly Vyacheslav becomes an acting chief doctor. Meanwhile an old woman with her daughter and granddaughter gets to the hospital with different injuries.
Ilya receives an offer from Moscow and is ready to go, as he promises to take Zhenya with him. Vyacheslav makes the life of other doctors and patients unbearable. Stepan is offended that Galya spends much time at work the way Zhenya did.
Ilya knows it’s a shame to leave his colleagues in such hard times. Zhenya feels even worse as she’s been working here her whole life, but it’s impossible to work with Slava. All of a sudden drugs started to disappear in the hospital and Slava tries to put it on Olga.
Zhenya and Ilya realize that they need to leave as soon as possible. There are new rules: the patients should receive only the first aid and no more difficult operations. Vyacheslav plans to move to commercial services. Meanwhile a young girl is taken to the hospital and two jealous young guys start a fight for her in the corridor.
Zhenya and Ilya tell the colleagues that Hippocrates’ operation was a success. Everyone is happy except Slava who doesn’t want the chief doctor back. Stepan and Galya live together happily and they plan a wedding trip. Vova is happy as well.
Zhenya and Stepan decide to tell their son everything while Ilya looks for a job for Zhenya in Moscow. There’s no place for her in his future clinic. Zhenya is upset they won’t work together, and soon she saves a young man with a toxication.
Zhenya and Stepan tell Roma that each of them has a new family. The boy is affronted by the lies he saw during the previous visit. Slava’s new orders almost cost an old patient his life. Patient’s daughter reports to the local newspaper about the accident.
It’s Ilya’s final working day and Slava is happy with this fact. Hippocrates returns to his office and everyone is happy. Zhenya refuses to leave and in the meantime there’s a real smasher in the newspaper about Slava. Zhenya saves a patient with breast impants’ rejection.
Zhenya is appointed as an admissions office administrator. Stepan in seriously injured while saving school kids from a chemical explosion, but Zhenya saves his life. Stepan tells Zhenya that he still loves her and that the wedding with Galya is a big mistake. Ilya learns that Lanskoy stands behind his new appointment…
